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Bottlebrush [UPDATED]

Named for its distinctive flowers, this evergreen has bright red flower spikes that are reminiscent of a bottle washer. The bottlebrush is often sold as a shrub, but can grow as a tree up to 25 feet in height. With patience, it can even be trained as an espalier.


Bottlebrush plants (Callistemon spp.) get their name from the spikes of flowers that bloom at the ends of the stems, bearing a strong resemblance to a bottle brush. Grow them as shrubs or small trees that grow up to 15 feet (4.5 m.). Most bottlebrush varieties bloom over a long summer season in shades of red or crimson. One exception is C. sieberi, which has light yellow flower spikes.

Callistemon bottlebrush care consists of regular watering while the tree is young and annual fertilization until it matures. Water young trees weekly in the absence of rain, applying the water slowly to saturate the soil as deeply as possible. A layer of mulch over the root zone will slow the evaporation of water and help prevent weeds. Use a 2-inch (5 cm.) layer of shredded hardwood or bark or a 3 to 4 inch (8 to 10 cm.) layer of light mulch such as pine straw, hay or shredded leaves.

Fertilize bottlebrush shrubs for the first time in their second spring. A 2-inch (5 cm.) layer of compost over the root zone makes an excellent fertilizer for bottlebrush. Pull back the mulch before spreading the compost. If you prefer to use a chemical fertilizer, follow the instructions on the label.

The common name "bottlebrush", perfectly describes this evergreen plant's bright red flower spikes. Hummingbirds love the flowers, and the plant is hardier than most bottlebrushes. The flowers are followed by small, woody capsules that look like bead bracelets on the bark, and which last for years. Offered as a shrub, bottlebrush can be trained as a tree to 15-feet or espaliered as a quick wall cover. It makes a nice screen or tall unclipped hedge. Pruning to develop several trunks and removing some lower branches can create a fine small specimen tree.

A good choice for a spot offering full sun, it will adapt to a variety of soils. Very drought-tolerant once established, bottlebrush tolerates any soil except very poor, alkaline, or poorly drained. Fertilize regularly to maintain good flower color and dark green foliage. Suckers from the trunk need to be removed periodically to maintain tree form.

Cancer therapies often have narrow therapeutic indexes and involve potentially suboptimal combinations due to the dissimilar physical properties of drug molecules. Nanomedicine platforms could address these challenges, but it remains unclear whether synergistic free-drug ratios translate to nanocarriers and whether nanocarriers with multiple drugs outperform mixtures of single-drug nanocarriers at the same dose. Here we report a bottlebrush prodrug (BPD) platform designed to answer these questions in the context of multiple myeloma therapy. We show that proteasome inhibitor (bortezomib)-based BPD monotherapy slows tumour progression in vivo and that mixtures of bortezomib, pomalidomide and dexamethasone BPDs exhibit in vitro synergistic, additive or antagonistic patterns, respectively, distinct from their corresponding free-drug counterparts. BPDs carrying a statistical mixture of three drugs in a synergistic ratio outperform the free-drug combination at the same ratio as well as a mixture of single-drug BPDs in the same ratio. Our results address unanswered questions in the field of nanomedicine, offering design principles for combination nanomedicines and strategies for improving current front-line monotherapies and combination therapies for multiple myeloma.

Honeybees love the blossoms as well. Though thebees are busy doing their job, many people are afraid of them so don'tplace this plant right next to a door or too close to a walkway.Another form of bottlebrush is the dwarf shrub "Little John" which can be kept about 3 feet. And the beautiful weeping bottlebrush tree is a popular small landscape tree.

FIRST IMPRESSIONS: Elymus hystrix is a clump forming cool season perennial grass. Plants form loose upright tufts of rough textured bright green blades. In summer pale green bottlebrush like inflorescences are displayed above the foliage. As seed matures the attractive spikelets develop a straw color. This is among the most shade tolerant native grasses. Plants thrive in part sun, part shade or shade and moist, average or dry soil.

The Bottle Brush tree (Callistemon), belongs to the Myrtaceae family. Bottlebrush trees are quite similar (and closest) to the Paperbark melaleucas, who also have flower spikes shaped like a bottlebrush.

I treated myself to a bottlebrush tree about 3 or 4 weeks ago and although it has plenty of blossom there is no sign of bottlebrushes. I did notice a week after I had bought mine that the remaining plants from the same batch as mine all had little bottlebrushes. I have it in my back garden which has the sun all day in good weather. I have also given it miracle-gro. Please can anyone help I am so disappointed.Thanks Jackie.p.s will the slugs attack it

Some plants have colorful but unusual flowers, making them interesting as well as attractive. The bottlebrush plant (Callistemon spp.) is that type of plant, producing cylindrical, fuzzy-looking, red flower clusters that give the plant its name. Bottlebrush is a sun-loving plant that puts on its best floral display in a sunny spot. It is hardy in U.S. Department of Agriculture (USDA) plant hardiness zones 8b through 11, depending on the species.

A sun-loving plant that is native to Australia, bottlebrush does best and produces the greatest number of flowers in a location exposed to full sun for most of the day. A few hours of late-afternoon shade won't hamper flowering significantly, but the plant is not a good choice for a fully shaded spot. The bottlebrush plant is a shrub that grows 3 to 20 feet tall, depending on the species, and can be pruned to grow as a small tree. Its flower clusters contain many tiny, red flowers encircling the stems, with each flower producing many long stamens that resemble fuzzy bristles.

Some bottlebrush varieties are compact and can do well as container plants, making it possible to overwinter them indoors in cold regions outside their hardiness zones. Those plants can be kept outdoors in a sunny spot from late spring through early fall but should be taken indoors when temperatures fall below 60 degrees Fahrenheit. During winter, a container-grown bottlebrush needs a brightly lit indoor spot and does well in a south- or west-facing window. When keeping the plant indoors, avoid placing it near a drafty door or window because cold air can damage the plant.

The bottlebrush plant is quite adaptable to any type of garden soil but grows best in a sandy loam that drains well. If your soil contains clay and tends to hold water, add some fine sand when planting a bottlebrush to increase the soil's drainage. The plant needs only an average amount of water and tolerates drought quite well once it is established in its site. In regions with cool winter weather, mulching the plant with a 2- to 3-inch thick layer of organic mulch can help protect its roots from winter damage. Watering it well as cold weather approaches also can prepare the plant for winter and help it survive without ill effects.

Several species of bottlebrush plant generally are available at garden centers. All thrive and bloom well in full-sun locations. The crimson bottlebrush (Callistemon citrinus), also known as lemon bottlebrush, is 3 to 12 feet tall while the stiff bottlebrush (Callistemon ridigus) is an erect shrub that can reach a height of 3 to 8 feet. Both plants have bright-red flowers. Crimson bottlebrush is hardy in USDA zones 8 through 10, and stiff bottlebrush is hardy in USDA zones 9 and 10. The weeping bottlebrush (Callistemon viminalis) grows as a small tree and reaches a height of about 20 feet tall at maturity. Its branches arch gracefully toward the ground, and its scarlet flower clusters hang from the tips of the branches, swaying in breezes. Weeping bottlebrush tolerates hot sun especially well and is hardy in USDA zones 9 through 11.

Fluorescent probes, glowing tags that can be attached to a variety of biomolecules, are ubiquitous in the study of biological systems. Chemists at Carnegie Mellon University have developed a new polymer-based probe, inspired by a bottlebrush, that can hold thousands of fluorescent molecules, making it 10 times brighter than current technology. Brighter probes like this will allow scientists to detect very low levels of protein expressed in cells. Their results are published in ACS Central Science.

Researchers in the labs of Krzysztof Matyjaszewski, the J.C. Warner University Professor of Natural Sciences, Bruce Armitage, professor of chemistry and co-director of the Center for Nucleic Acids Science and Technology, and Subha R. Das, associate professor of chemistry, combined their expertise in polymer synthesis and DNA chemistry to create a brighter probe that allows scientists to monitor sparsely expressed proteins. The chemists found their inspiration in the many bristles of the bottlebrush.

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